I got a server 500 Error when accessing the akismet spam filter. Checking the logs and I could see the error was
ModSecurity: Output filter: Response body too large (over limit of 524288, total not specified)
To correct this edit this file
/etc/httpd/modsecurity.d/modsecurity_crs_10_config.conf
Look for the line
SecResponseBodyLimit 524288
I just added a leading 1 to the number and restarted apache.
Just re-read the title and it sounds like science fiction B movie title.. Oh well.
After running this for a while and having played with all the possible options in Wordpress here is my final Mod_Security custom file.
Mod Security exceptions for WordPress, yet another addition.
Found an interesting Blog here covers false positives and creating your own rules.
I have started a page with rough notes on creating rules here. This is taken directly from a pdf from the Modsecurity site and I will update it with real examples.